INTRODUCTION TO BIOINFORMATICS

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=课程主页:,

 

   Instructor: Tolga CAN

   Added: 18 November 2009

 

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Topic outline

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  General

   

  INTRODUCTION TO BIOINFORMATICS

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  Topic 1

  Introduction to Bioinformatics

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  Topic 2

  Introduction to biology, biological databases, and high-throughput data sources. Overview of bioinformatics problems.

  Pairwise sequence alignment algorithms: Dynamic programming

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  Topic 3

  Statistical significance of alignments - Part I

  Statistical significance of alignments - Part II

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  Topic 4

  Suffix Trees, Suffix Arrays

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  Topic 5

  Patterns, Profiles, and Multiple Alignments

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  Topic 6

  Hidden Markov Models

  Week 5 Lecture Slides Continued

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  Topic 7

  Multiple Sequence Alignment Algorithms

  Week 5 Lecture Slides Continued

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  Topic 8

  Midterm Review and Midterm Exam

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    Phylogenetic trees
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  Topic 9

  Introduction to protein structures

  Structure Prediction

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  Topic 10

  Protein Structure Prediction (continued)

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  Topic 11

  Protein Structure Prediction (continued)

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  Topic 12

  Structural Alignment of Proteins

  (lecture notes continued)

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  Topic 13

  Microarray data normalization, analysis

  Clustering techniques

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  Topic 14

  Introduction to Systems Biology

  Gene regulatory networks

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  Topic 15

  Construction and Analysis of protein networks:

  Monte Carlo Sampling, Random Walks on Graphs

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    Final review